Feeding induced by intracranial and intravenously administered 2-deoxy-D-glucose
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منابع مشابه
Brain adrenergic system in the feeding response induced by 2-deoxy-D-glucose.
Brain adrenergic system in the feeding response induced by Z-deoxy-D-glucose. Am. J. Physiol. 223(4) : 945-950. 1972.-A reliable eating response was obtained in rats on injection of the glucose analogue, 2-deoxy-n-glucose (Z-DG; 750 " g/kg, ip), which produces decreased intracellular glucose utilization of most tissues and particularly of brain. Intraventricular administration of an a-adrenergi...
متن کاملFeeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat.
Feeding was induced with lateral intracerebroventricular (ICV) injections of 2-deoxy-D-glucose (2-dg), a glucose analogue causing glucoprivation. Feeding increased rapidly by an average of 2.6 g following ICV 2-DG (2.9 or 5.8 mg per rat), but did not increase after ICV D-glucose or sucrose. At the same doses, 2-DG did not increase feeding when given peripherally. Core temperature dropped in a d...
متن کاملAntiangiogenic Activity of 2-Deoxy-D-Glucose
BACKGROUND During tumor angiogenesis, endothelial cells (ECs) are engaged in a number of energy consuming biological processes, such as proliferation, migration, and capillary formation. Since glucose uptake and metabolism are increased to meet this energy need, the effects of the glycolytic inhibitor 2-deoxy-D-glucose (2-DG) on in vitro and in vivo angiogenesis were investigated. METHODOLOGY...
متن کاملThreshold doses of 2-deoxy-D-glucose for hyperglycemia and feeding in rats and monkeys.
SMITH, GERARD P., JAMES GIBBS, ALAN J. STROHMAYER, AND PETER E. STOKES. Threshold doses of 2-deoxy-D-glucose for hyper$ycemia and feeding in rats and monkeys. Am. J. Physiol. 222(l): 77-81. 1972.~Injection of the glucose analogue, 2-deoxy-nglucose (2-DG) , into intact mammals produces a metabolic \tate of glucoprivation characterized by extracellular hyperrlycemia and decreased intracellular gl...
متن کاملInhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose.
Pseudorabies virus-induced cell fusion in rabbit kidney cells can be prevented by Concanavalin A added early after infection. The infected cells are not agglutinated and the infectivity of cell-free virus is not reduced. Sera from productively infected animals also inhibit polykaryocytosis, whereas a hyperimmune serum directed against virus structural components has no effect. 2-Deoxy-d-glucose...
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ژورنال
عنوان ژورنال: Physiological Psychology
سال: 1974
ISSN: 0090-5046
DOI: 10.3758/bf03333031